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pentobarbital decreases levels of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Solid CYP3A4 inducers can cut down panobinostat levels by ~70% and bring about treatment failure.Can only be sold in premises which can be registered pharmacies and by or underneath the supervision of the pharmacistThis limited

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Barbiturates can result in fetal harm when administered to a pregnant woman. Retrospective, case-controlled research have proposed a connection in between the maternal consumption of barbiturates and a higher than anticipated incidence of fetal abnormalities. Pursuing oral or parenteral administration, barbiturates commonly cross the placental barr

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